Anno 2205 Frontiers-rune [verified]

To unlock and sustain the Synthetic population, you must master the supply chains in the new sectors, as they require resources unique to the Frontiers maps.

This is a true endgame challenge. Synthetics are a man-machine hybrid workforce that demands rare materials but offers incredibly high productivity. Unlike humans, they don't pay taxes, but they also don't require many of the basic social services like stadiums or security, provided you can meet their complex industrial needs. Anno 2205 Frontiers-RUNE